Abstract
Nowadays, inflammatory cell sin peripheral blood are considered as prognostic factors in different malignan-cies. The aim of this study was to identify the prognostic value of pretreatment blood inflammatory biomarkers for patients undergoing surgery for I–II stages of non-small-cell lung cancer (NSCLC). Methods. A single-center retro-spective review from 2003 to 2017 enrolled 403 patients with early stages of NSCLC who underwent surgical resec-tion in our hospital. Results. Univariate Cox proportional hazards analysis showed that age (>70), high level of the systematic immune-inflammation index (>489.67 • 109/l) and neutrophil to lymphocyte ratio (>2.03 • 109/l) were identified as the independent prognostic factors (OR 1.908 CI: 1.361–2.677; 1.735 CI: 1.018–2.956 and 1.626 CI: 0.994–2.659 respectively р<0.05). Conclusions. Pre-operative level of blood hematological biomarkers may serve as a useful and accessible prognostic indicators for predicting outcomes in patients with I– II stages of NSCLC.
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