Abstract
Background & objective: Stroke is a dreadful health hazard all over the world as well as in our country and one of the leading causes of mortality & morbidity. The relationship between serum C-reactive protein (CRP) level and post stroke outcome is not well studied especially in Bangladesh. We were interested to study this relationship in our country. Materials & methods: A cross sectional prospective study was performed on 50-stroke patients. Serum CRP & Lipid profile was determined. Post stroke outcome was measured by modified ranking scale (good outcome, score within 0 – 2 & bad outcome, score within 3 – 6). The subjects were divided in two groups, CRP level above or below 10 mg/L. Statistical analysis was performed by using SPSS software. Chi-square test & Spearman’s rho correlation test was done to see the level of significance. Results: Mean serum CRP level was 9.69 mg/L that was higher than normal subjects. Correlation analysis between serums CRP level of stroke patients with post stroke outcome was found to be positively correlated (r = 0.598/p<0.01). Conclusion: Serum CRP level may be used as a prognostic marker in stroke patients and it helps to make necessary management plan to physician. DOI: 10.3329/bjms.v10i1.7316 Bangladesh Journal of Medical Science Vol.10 No.1 Jan 2010 pp.29-33
Highlights
The term cerebrovascular disease denotes any abnormality of brain caused by a pathologic process of blood vessels
We found significantly (p< 0.001) higher level serum C-reactive protein (CRP) in the group B than group A
We found in group B significantly (p< 0.05) higher level modified Rankin Scale (MRS), total cholesterol, LDL and Low level HDL than group A
Summary
The term cerebrovascular disease denotes any abnormality of brain caused by a pathologic process of blood vessels. Cerebrovascular disease is the 3rd leading cause of death in the United States. It is the most prevalent neurolgic disorder in terms of both morbidity & mortality. Cerebrovascular diseases can cause death & disability by ischemia, from occlusion of blood vessel (producing cerebral ischemia &infarction) or hemorrhage through their rupture[3]. The relationship between serum C-reactive protein (CRP) level and post stroke outcome is not well studied especially in Bangladesh. Correlation analysis between serums CRP level of stroke patients with post stroke outcome was found to be positively correlated (r = 0.598/p
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