Prognostic influencing factors of posterior communicating aneurysm associated with oculomotor nerve palsy

Abstract

Objective To investigate the prognosis of patients with posterior communicating aneurysm associated with oculomotor nerve palsy in 12 months, and analyze the possible prognostic influencing factors. Methods A prospective clinical study was conducted in 39 patients with posterior communicating aneurysm associated with oculomotor palsy. The patients were followed up for 12 months after surgery, and the prognosis of oculomotor palsy symptoms was evaluated. Results In 39 patients, 16 cases were treated by craniotomy clipping, and 23 cases were treated by intravascular embolization. Univariate Logistic analysis result showed that the prognosis of oculomotor palsy symptoms in patient with age ≤ 60 years was significantly better than that in patient with age >60 years, the prognosis of the patients with operation timing ≤ 14 d was significantly better than that of patients with operation timing > 14 d, and there were statistical differences (P 0.05). Multifactor Logistic analysis result showed that age and operation timing were the independent prognostic influencing factors of oculomotor palsy symptoms (OR = 6.574 and 32.510, 95% CI 1.119 - 38.640 and 2.869 - 368.363, P < 0.05 or <0.01). Conclusions Surgical treatment of aneurysms can improve the prognosis in patients with posterior communicating aneurysm associated with oculomotor nerve palsy, and the prognosis of patients with young age and early surgical treatment is relatively better. Key words: Oculomotor nerve diseases; Aneurysm; Prognosis; Prospective studies