Abstract
Purpose/Objective: Survivin is a member of the inhibitor of apoptosis family that has been implicated in both regulating cell division and in suppressing apoptosis. Survivin is expressed in most of human malignant tumors. Overexpression of cytoplasmic survivin correlate with unfavorable prognosis in many malignant tumors. However, prognostic value of the nuclear survivin expression is still equivocal. This study is the first report investigating the prognostic value of survivin expression in cervical cancer treated with radiation therapy.
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