Abstract
Light chain involvement is observed in almost every newly diagnosed multiple myeloma (MM). While 15-20% of MM patients suffer of a light chain only myeloma, 70-80% of IgA and IgG myeloma present an additional abnormal free light chain ratio (FLCR), too. Due to a shorter half life period a rapid reduction of the involved light chain (iFLC) could be of prognostic value in order to personalize and optimize treatment options.
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