Abstract
Aim of the current study was to analyse the impact of atrial fibrillation (AF) on prognosis in patients with cardiogenic shock (CS) complicating acute myocardial infarction (AMI), which has never been investigated yet. The current analysis is a substudy of the IABP-SHOCK II trial. Patients were grouped according to the presence or absence of AF. The primary endpoint was all-cause mortality at 30-day follow-up. Secondary endpoints included all-cause mortality, recurrent myocardial infarction, repeat revascularisation, and stroke at 12months. AF was documented in 28.2% (n=169) of all 600patients initially enrolled in the IABP-SHOCK II trial. There were no significant differences with respect to mortality at 30days and 12months between patients with and without AF (p=0.81, p=0.74). Similarly, the rates of recurrent myocardial infarction, repeat revascularisation, and stroke did not differ between groups (all p > 0.05). There was no interaction of intraaortic balloon counterpulsation (IABP) and no IABP in patients with or without AF with respect to clinical outcome at 30days and 12months (p > 0.05). AF is not associated with clinical outcome at 30days and 12months in CS complicating AMI.
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