Abstract
Kidney transplant (KT) programs have extended recipient eligibility to those who were previously excluded due to advanced age. We aimed to determine the outcomes of the patients ≥70years undergoing KT and investigate factors predicting survival. Two thousand six hundred and twenty-four KT patients between 2003 and 2013 at two institutions were divided into two groups; those ≥70years (n=300) and those <70years (n=2324) at the time of KT. Patient survival at 1, 3, and 5years was 95%, 86%, and 77% in ≥70years of age group and 98%, 95%, and 90% in the <70years group (P<.001). When graft loss due to death was censored, graft survival was not significantly different between the two groups (P=.18). On multivariable analysis, the significant predictors of inferior survival in patients ≥70years included: body mass index (BMI)>30kg/m(2) (hazard ratio [HR] 1.07; P=.01), panel reactive antibody (PRA)>20% (HR 2.38; P=.01), previous coronary artery bypass grafting (CABG; HR 1.95; P=.03) and peripheral vascular disease (PVD; HR 2.60; P=.04). Acceptable outcomes can be achieved in KT recipients ≥70years. Caution should be used when listing these patients if they have BMI>30kg/m(2) , PRA>20%, CABG or PVD.
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