Abstract
ABSTRACTBackground: Colorectal cancer is the third most common cancer in the world. In Brazil, it is the leading cause of cancer in the gastrointestinal tract. Aim: To evaluate the preoperative, perioperative, and postoperative risk factors for recurrence and overall survival of patients with left colon cancer operated during a ten-year period. Methods: Patients with left colon cancer surgically treated underwent clinical preoperative workout and cancer staging. The following factors were studied: gender, age, tumor location, T stage, lymph node yield, N stage, M stage, histological type, and tumor differentiation. It was analyzed the influence in five-year overall survival. Results: A total of 173 patients underwent left colectomy for colon cancer. There was a slight predominance of male gender with 50.9%. The mean age was 60.8 years old. Fifteen (8.7%) tumors were located at splenic flexure, 126 (72.8%) at sigmoid colon, and 32 (18.5%) at descending colon. The median length of hospital stay was seven days. Mean survival was 47.5 months. At 60 months seven patients (4%) lost follow-up, 38 patients (21.9%) deceased and 135 patients (78%) were alive. Overall survival time was 48 months. Conclusion: Advanced stages (T3-T4, N+ and M+) were the only factors associated with poor long term survival in left colon cancer.
Highlights
Colorectal cancer (CRC) is the third most common cancer in the world[20]
Left colectomy for the cancer localized at the descending and sigmoid colon is the procedure of choice for complete oncologic resection and favorable prognosis[3]
The aim of the present study was to evaluate the pre, peri- and postoperative risk factors for recurrence and overall survival of patients with left colon cancer operated during a ten-year period in a universitary service
Summary
Colorectal cancer (CRC) is the third most common cancer in the world[20]. Radical surgery involves the removal of the intestinal segment involved by the tumor, which must include an adequate margin of resection and complete loco regional lymphadenectomy[23]. Complete removal of the tumor along with the major vascular pedicle and the lymphatic drainage, either by laparotomy or laparoscopy is the best curative option for patients with localized colonic cancer[8,14,15]. Left colectomy for the cancer localized at the descending and sigmoid colon is the procedure of choice for complete oncologic resection and favorable prognosis[3]. Despite the complete oncologically surgery, the survival rates are 65-83%3,7
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