Prognostic analysis of extended field intensity-modulated radiation therapy for cervical cancer

Abstract

In recent decades, accurate radiotherapy has developed rapidly, and the application of intensity-modulated radiation therapy (IMRT) in gynecologic malignancies has increased gradually in the past ten years. Many studies have shown a high rate of occult abdominal aortic lymph node metastasis in patients with advanced cervical cancer, while pelvic and abdominal aortic lymph node status are important prognostic factors in cervical cancer patients. Conventional prophylactic extended field radiotherapy has the characteristics of severe gastrointestinal side effects, and synchronic chemotherapy is also controversial. The optimal dose of radiation therapy for metastatic pelvic and abdominal aortic lymph nodes is still controversial. This paper mainly analyzed the effect of prophylactic extended conformal radiotherapy with concurrent chemotherapy on the prognosis of cervical cancer and the dose-effect relationship of lymph node positive region. Key words: Cervical neoplasm/intensity modulated radiation therapy; Extended field radiotherapy; Concurrent chemotherapy; Lymph node; Survival rate