Abstract

The prognosis for patients who underwent hepatectomy for primary liver cancer that was complicated by liver cirrhosis was evaluated by the stage of the tumor and preoperative liver function. The cumulative 5-year survival rate for patients with stage I and II liver cancer was more than 40%, therefore, hepatectomy was regarded as effective therapy for liver cancer complicated by liver cirrhosis.The values of ICGRmax, ICGK, hepaplastin test and gamma globulin were related to the early postoperative prognosis.Many patients who underwent major hepatectomy died of liver failure. Significant defferences in cumulative survival rate were noted between patients with good and poor liver function expressed by ICGRmax and ICGK values, and the prognosis for patients without thrombocytepenia was better than for those with thrombocytepenia. Furthermore, the volume of the resected liver and the prothrombin time influenced the prognosis for hepatectomized patients.Prognostic scores were formed by giving points to the factors mentioned above, and the prognostic score is useful for predicting the long-term prognosis for hepatectomized patients with the complication of liver cirrhosis. The evaluation of preoperative liver function is important for deciding whether or not hepatectomy is indicated and for selecting the operative methods.

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