Abstract

Corona virus disease 2019 (Covid-19) is an acute respiratory illness caused by the Corona virus. Corona virus 2 (SARS-CoV-2) is a continuing global health crisis that has harmed the physiological and psychological health of people in over 200 countries worldwide. The current study performed a narrative review of its origin, epidemiology, transmission, clinical parameters, effects on mental health, management, vaccines and their trails, and future perspectives. The ease with which humans may transmit information to one another is unnoticeable in the early stages, making COVID-19 both terrifying and remarkable, but as time progresses, it can be managed successfully with the available therapies to some extent. Based on the condition and co-morbidities, therapeutic management is used in the pandemic situation, which includes drugs like antivirals, chloroquine and hydroxychloroquine, convalescent plasma therapy, Azithromycin, Corticosteroids, Cytokine’s, and oxygen therapy. Strategies such as self-quarantine, social isolation, and 70-day nationwide and state-by-state lockdowns in India aided in slowing the virus's spread, which may have been catastrophic otherwise. However, there are no clinically approved safer vaccines until the end of 2020. Several businesses have taken the lead in producing COVID-19 vaccines and came up with vaccines like Pfizer, Moderna from the US and UK, Covaxin, and Covishield from India, and vaccination programs began in India for targeting more than 300 million people.

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