Abstract

Prognostication is inherent in essentially all decision making in cancer care. The clinician is usually silently integrating factors about the patient's cancer diagnosis with considerations about the efficacy, toxicity, and risks of treatment all in the context of the patient's age, overall health, and comorbidities. This paradigm is especially apparent when making adjuvant therapy decisions and balancing the risk of recurrence with the statistical risk reduction of treatment and coexisting patient's health issues.

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