Abstract
In a prospective study, we compared the prognosis for survival, handicap, and recurrence of stroke in 103 patients with a first-ever lacunar infarct, presumably due to small-vessel obstruction, with that in 94 patients who had a first-ever superficial infarct associated with large-vessel disease. Patients with lacunar infarction had better survival, as shown by Kaplan-Meier analysis, and less disability than patients with superficial infarction, whereas the difference in risk of recurrent infarction was not statistically significant. Six of the 7 (86%) recipient infarcts in the lacunar infarction group were lacunar again, supporting the hypothesis that lacunar infarcts are usually caused by a local small-vessel obstruction.
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