Abstract
Summary. Metabolic clearance rate (MCR), production rate (PR) and plasma protein-binding of progesterone were measured during embryonic diapause and after ovariectomy in the tammar wallaby. The effect of ovine prolactin and LH on the secretion of progesterone by the quiescent corpus luteum in vitro was also examined. During embryonic diapause, a low plasma progesterone concentration of 196 \m=+- 24 (s.e.m.) pg/ml (n = 7) was associated with a low PR of 20\m=.\2 \m=+- 1\m=.\4 ng/kg/min and a high MCR of 111\m=.\0 \m=+- 7\m=.\6ml/kg/min. Similar values were obtained for the 4 animals ovariectomized 9 or 12 months previously (plasma progesterone = 156 \m=+- 14 pg/ml; MCR = 147 \m=+- 16 ml/kg/min; PR = 20\m=.\4 \m=+- 2\m=.\2
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