Abstract
Purpose: Due to the limited regenerative capacity of the meniscus, (partial) meniscectomy is often the treatment of choice. Consequential loss of contact area and abnormal distribution of forces lead to osteoarthritis. Therefore, there is an unmet clinical need for meniscus regeneration. Recently the presence of multipotent mesenchymal stromal (stem) cells (MSCs) or progenitor cells in different intra-articular tissues, for example in articular cartilage has been acknowledged. If progenitor cells are also present in the meniscus, they could be targeted for meniscus regeneration.
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