Profiling of odontogenic tumors in western Uttar Pradesh population in India

Abstract

Objective: This institutional study was sought to determine the relative frequency of odontogenic tumors (OTs) in a western Uttar Pradesh population and to compare these data with previous reports. Study Design: In this retrospective study, all the accessioned cases were retrieved from the histopathology records of Subharti Dental College and Hospital between January 2003 and December 2015. Lesions with histological diagnosis of OTs (based on the World Health Organization classification, 2005) were analyzed. Clinical data were reviewed, and microscopic diagnoses were confirmed for cases in which diagnoses were ambiguous. The relative incidence of each tumor type, patient age, gender, and site of occurrence are compared with similar reports from other selected large series. Results: From a total of 3182 oral biopsies accessioned during 13-year interval, 255 lesions were diagnosed histopathologically as OTs, which constituted 8.01% of all the oral biopsies. Of these cases, 98.43% of the tumors were benign. The most frequent histological type was keratinizing cystic OTs (41.96%), followed by ameloblastoma (34.50%) and while odontomas, generally regarded as the most frequent OT in many large series, only accounted for 7.45%, the third most common tumor in the present study. In general, the OTs showed a predilection for the mandible and the posterior regions of the jaws. Males outnumbered females for benign tumors while the reverse was true for malignant tumors. Conclusions: OTs show a definite geographic variation. In western Uttar Pradesh population in India, the most frequent OTs had a comparatively younger age predilection.