Profile of Stevens-Johnson syndrome and toxic epidermal necrolysis patients in the inpatient hospital installation of Dr. Soetomo general hospital Surabaya from January 2019 – December 2021

Abstract

Background: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis are significant health issues due to their severe complications. Factors like age, clinical symptoms, and underlying etiology play crucial roles in patient management. Therefore, it is important to review further the background or profile of the patients. This is the basis for conducting this study. This research aims to provide an overview of patients with SJS-TEN in the Inpatient Installation of RSUD Dr. Soetomo Surabaya, aiming to aid in prevention and management. Aim: Providing an overview of the profile of patients with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in the Inpatient Installation of Dr. RSUD. Soetomo Surabaya Methods: The study analyzed medical records of patients with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis at RSUD Dr. Soetomo Surabaya from 2019-2021, analyzing parameters such as gender, age, symptoms, etiology, comorbidities, and length of stay. Results: The study found 28 cases of SJS-TEN, with 15 males (53.6%) and 13 females (46.4%). The highest prevalence was in the age group 19-44 years old as we called adult (35.7%). Most patients had multiple comorbidities, with common clinical symptoms including palpebral edema, multiple erythematous macules, conjunctival erythema, and fever. Most patients were classified as SCORTEN 1, with 71.4% taking multiple drugs. Most patients experienced multiple complications but experienced improvement and continued treatment through outpatient care (57.1%).