PROFILE OF ORAL MANIFESTATIONS OF GRAFT VERSUS HOST DISEASE

Abstract

Objective To identify the profile of the oral manifestations of GVHD, favoring early diagnosis to determine the most appropriate treatment for the severity of the disease. Study Design Our study performed a retrospective analysis of oral GVHD images in patients´ post-HSCT and clinical information. Results The retrospective evaluation of medical records showed an important variation of lesions, the most cited being lichenoid lesions, erythema, and hyperkeratotic plaques, as well as their locations, frequencies, and symptoms. Conclusion It is evident that GVHD manifests itself in different ways in the oral cavity. Therefore, understanding its possible clinical presentation well and knowing how to classify it in terms of severity becomes important not only to determine the most appropriate prognosis and treatment, but also to differentiate it from lesions with malignant potential. To identify the profile of the oral manifestations of GVHD, favoring early diagnosis to determine the most appropriate treatment for the severity of the disease. Our study performed a retrospective analysis of oral GVHD images in patients´ post-HSCT and clinical information. The retrospective evaluation of medical records showed an important variation of lesions, the most cited being lichenoid lesions, erythema, and hyperkeratotic plaques, as well as their locations, frequencies, and symptoms. It is evident that GVHD manifests itself in different ways in the oral cavity. Therefore, understanding its possible clinical presentation well and knowing how to classify it in terms of severity becomes important not only to determine the most appropriate prognosis and treatment, but also to differentiate it from lesions with malignant potential.