Abstract
Background HIV/AIDS is a global pandemic with cases reported from virtually every country. The CD4 cells are the primary target cells for HIV. The hallmark of HIV disease is a profound immunodeficiency resulting from a progressive quantitative and qualitative deficiency of CD4+ T cells. As CD4 count decreases, opportunistic infections (OIs) manifest. HIV infection progressing to AIDS is associated with many OIs.
Highlights
HIV/AIDS is a global pandemic with cases reported from virtually every country
HIV infection progressing to AIDS is associated with many opportunistic infections (OIs)
ResultsThis study involved a descriptive study and tuberculosis (43.9 %) was found to be most common opportunistic infections (OIs) seen in patients with mean CD4 count 360 ± 56cells /μL , followed by candidiasis (14.6 %) with mean CD4 count 324 ± 42cells/μL , diarrhea due to coccidian parasite infection (8.5%) with mean CD4 count 97±15 cells/μL, cryptococcal meningitis (3.65 %) and Pneumocystis jiroveci pneumonia (3.65 %) with mean CD4 count 92 ± 6 cells/μL
Summary
HIV/AIDS is a global pandemic with cases reported from virtually every country. The CD4 cells are the primary target cells for HIV. The hallmark of HIV disease is a profound immunodeficiency resulting from a progressive quantitative and qualitative deficiency of CD4+ T cells. As CD4 count decreases, opportunistic infections (OIs) manifest. HIV infection progressing to AIDS is associated with many OIs
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