Profile of Nasopharyngeal Cancer Patients in Otorhinolaryngology-HNS Department Haji Adam Malik General Hospital Medan During 2014-2016

Abstract

Introduction: Nasopharyngeal cancer is the most common malignant tumor found among any other malignant ENT tumors in Indonesia. Nasopharyngeal cancer (NPC) is a unique epithelial malignancy arising from the superior aspect of the pharyngeal mucosal space associated with latent Epstein-Barr virus infection in most cases. Nasopharyngeal cancer is generally more common in Southeast Asia. The five countries with the highest incidence of nasopharyngeal cancer in the world were China, Indonesia, Vietnam, India, and Malaysia, respectively. Objective: The aim of this study was to investigate the effects of characteristics of distant metastases in nasopharyngeal cancer patients in the Otorhinolaryngology-HNS Department Haji Adam Malik General Hospital Medan during 2014-2016. Methods: This was an observational descriptive study with a cross-sectional design in a retrospective manner, where this study aimed to look at how the characteristics of distant metastasis in patients with nasopharyngeal cancer Results: From all over the subject, distant metastases most common in liver 52 (24.5%), follow by Renal function impairment 18 (8.5%), Lung metastasis 10 (4.7%), Heart Impairment 10 (4.7%). Conclusion: Most people with nasopharyngeal cancer come from the age group 38-47 years (31.6%). Most sufferers of nasopharyngeal cancer are men (69.3%). The state of disease in nasopharyngeal cancer with the highest incidence rate is stage IV (63.7%). Most organ impairment found in patients with nasopharyngeal cancer is liver disorder (24.5%).