Abstract
Background: Oxidative stress is associated functional changes after myocardial infarction (MI) in rats. Studies have reported potential benefits in cardiac function using cellular therapy (CT) after MI. However, whether these potential beneficial effects modulate favorably oxidative pathways is unexplored. Objectives:To assess oxidative stress profile 48h post-experimental MI, with and without adjuvant bone marrow (BM) CT. Methods: Male Wistar rats, 8-week-old, weighting 315 ± 0.043g, (n = 10/group) divided in four groups: 1) Sham-operated (S); 2) MI, 3) Sham-operated + treatment with cells (ST) and 4) MI + treatment with cells (MIT).
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