Abstract
This work investigates the quality of emulsions obtained from fast emulsification in a microsystem implemented at high throughput. The aim is to manufacture oil in water (O/W) emulsions in which bioactive ingredients could be encapsulated. These emulsions may be of interest for cosmetic, nutraceutical and/or pharmaceutical applications. A microsystem based on an improved cross-slot configuration is tested for production of emulsions with various formulations in a range of flow rate comprised in 100−600 mL/min. Dispersed lipid phase consists mainly in sunflower oil. The continuous aqueous phase is a Non-Newtonian fluid as it includes xanthan in order to stabilize the emulsions. Several commercial surfactants are also used to stabilize the emulsions. Their stability is examined during a storage period of approximately 30 days. For most tests, the evaluation of emulsions is based on a comparison with emulsions produced from a commercial laboratory rotor stator emulsifier. The results show only a few slight differences between the characteristics of emulsions generated in continuous in the microsystem and those obtained from the batch rotor-stator emulsifier. The results are therefore mostly comparable, which leads to the conclusion that microsystems can offer an interesting alternative to the small-scale production of emulsions.
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