Abstract
Serial cultivation of cells obtained from the human pituitary is described. Somatotropin, corticotropin, and gonadotropin have been detected in these cultures. Two of the cell lines have produced gonadotropin, both FSH and ICSH, when in suspension culture, and one, S4374-M, has been frozen and recultivated in both stationary- and suspension types of culture with media containing 10% of human, equine or bovine serum, with resumption of production of hormone. The gonadotropin-producing cells have the microscopical appearance of a chromophobe type of pituitary cell and have a characteristic appearance when stained by the iron-PAS method. These cells are heteroploid with a chromosome count in narrow range with modality at 79.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
