Abstract
In the present study, 46S6 bioactive glasses with composition 46 SiO2% –24% Na2O – 24% CaO – 6% P2O5in weight percent were synthesized through melt-derived process using alkali extracted silica from rice hull ash and commercial silica. Bioactive glasses were incubated in SBF (simulated body fluid), before and after immersing in SBF, characterized by SEM to investigate degradation and apatite formation. Also bioactivity tests such as cell culture, cell viability and cytotoxicity, differentiation, mineralization and alkaline phosphatase assay have been performed. Results showed that 46S6 bioactive glasses from rice hull ash silica had better metabolic activity and viability than that obtained from commercial silica.
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