Abstract

The metallic radionuclide 86Y was produced by irradiation of enriched 86SrCO 3 on a low-energy proton-only cyclotron. Irradiations up to 20 μA for 2 h were performed with 11 MeV protons using a water-cooled target mounting with circulating chilled helium. Experimental thick target yields of 26.7 mCi/μA yielded 24 mCi of 86Y in 2 h of bombardment at 10 μA. The difference in solubility products between Y(OH) 3 and Sr(OH) 2 allows the separation of 86Y from an alkaline strontium solution by using filter paper with an overall yield of 88±3%. The concentration of Sr in the final product was found to be on the order of 15 ppm when using 200 mg of target material as determined by ICP-MS analysis. The reactivity of 86Y was determined to be on the order of 1.5±0.8 Ci/μmol of DOTA. The enriched target material was recovered and converted to its original chemical form with an overall efficiency >90%.

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