Abstract
The technology of microbial conversion provides a potential way to exploit compounds of biotechnological potential. The red pigment prodigiosin (PG) and other PG-like pigments from bacteria, majorly from Serratia marcescens, have been reported as bioactive secondary metabolites that can be used in the broad fields of agriculture, fine chemicals, and pharmacy. Increasing PG productivity by investigating the culture conditions especially the inexpensive carbon and nitrogen (C/N) sources has become an important factor for large-scale production. Investigations into the bioactivities and applications of PG and its related compounds have also been given increased attention. To save production cost, chitin and protein-containing fishery byproducts have recently been investigated as the sole C/N source for the production of PG and chitinolytic/proteolytic enzymes. This strategy provides an environmentally-friendly selection using inexpensive C/N sources to produce a high yield of PG together with chitinolytic and proteolytic enzymes by S. marcescens. The review article will provide effective references for production, bioactivity, and application of S. marcescens PG in various fields such as biocontrol agents and potential pharmaceutical drugs.
Highlights
Chitin and its derivatives have numerous applications in the fields of environment protection, fine chemistry, and pharmacy [1,2,3,4,5,6,7,8,9,10,11]. Fishery processing byproducts, such as shrimp and crab shells, shrimp heads, and squid pens, are the main sources of chitin and chitosan which are conventionally prepared via chemical pretreatments of acid demineralization and hot-alkali deproteinization [1,5,9,11,12,13,14,15,16]
To cut down fermentation expenses, the inexpensive materials of shrimp heads, shrimp shells, crab shells, and squid pens have recently been evaluated as the sole C/N sources for the production of bioactive compounds [5,6,9,12,13,14,15,16,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74]
Chitin and protein-containing marine byproducts have been utilized as the sole C/N source by S. marcescens TKU011 for the simultaneous production of pigments have expanded (PGs) [59,60,61,62], chitinolytic enzymes, and proteolytic enzymes [36,37]
Summary
Chitin and its derivatives have numerous applications in the fields of environment protection, fine chemistry, and pharmacy [1,2,3,4,5,6,7,8,9,10,11]. The antimicrobial, Pigments of anti-parasite microbial origin have received much more attention in recent due toto their anti-cancer, and bioactivities confer the bacterial pigments with studies the potential be versatile applications in agriculture, food, cosmetics, textile, and pharmacy. The worldwide concern recently has been to extend and anti-parasite bioactivities confer the bacterial the potential be developed as inclination towards the use of natural materialspigments in place with of artificial ones to because of several pharmaceutical products [75,76,77,78].over. Chitin and protein-containing marine byproducts have been utilized as the sole C/N source by S. marcescens TKU011 for the simultaneous production of PG [59,60,61,62], chitinolytic enzymes, and proteolytic enzymes [36,37]. The uses of S. marcescens PG in several fields, especially as biocontrol agents, are comprehensively reviewed
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
