Process of Regeneration and Development of the Tissue Receptors Specificity

Abstract

Publisher Summary Development of the receptors is one of the most important but unsolved issue of sensory physiology. The growth of afferent nerve fibres produces nerve endings specific to the given tissue. A differentiated neurone possesses the specificity, which allows the growing nerve fibres to develop a selective connection with a tissue of certain biochemical nature at the periphery. Thus, the nerve fibers play a main role in the development of tissue receptors. The tissue develops specific receptors when innervated by any sensory fibres. Tissue receptor specificity could easily be traced in studies on peripheral nerves regeneration. When studying the process of receptor development, using not only morphological but also functional methods, it is very important to perform continuous observation of a single sensory element at various stages of its development. Thus, the Pacinian corpuscles of cat mesentery are well suited for a study of peripheral nerves regeneration.