Abstract

This paper presents an engineering vision and approach to automation of a complex batch process utilizing separate recipes for equipment preparation, intermediate and product operations in a flexible Multi-Product Bio-Technology batch manufacturing production facility. One of the more complex engineering activities in a batch plant (based on S88.01 standard) is unit definition and development of equipment boundaries to give the facility the appropriate modular structure (the process model) necessary for processing flexibility. In a bio-technology plant, units have more than one status which also can expire. Because of this, recipes may only be allocated to units with an acceptable status. Methods to deal with this are described with emphasis on the need to define and design recipe structures together with modular equipment in order to achieve an agile operating environment with optimum recipe scheduling capabilities.

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