Abstract
A new home-made UV photochemical reactor (95 cm of irradiation zone) consisting of a 12 parallel quartz tubes flow reactor, PQT6 (95 cm under irradiation and an internal diameter of 0.6 cm) was assembled to perform photochemical transformations in continuous-flow. PQT6 was evaluated for the photoreaction of 1-allylpyridinium bromide (1a) to 6-allyl-6-azabicyclo[3.1.0]hex-3-en-2-ol (2a), in a continuous process. This technology provides reduced reaction times, continuous production of 2a, and a productivity of 129 mg h−1, corresponding to 1.94 g of isolated 2a after 15 h of irradiation.
Highlights
BBiiccyycclliicc aazziirriiddiinneess ((αα--hhyyddrrooxxyyccyyccllooppeenntteennoo--aazziirriiddiinneess)) pprreeppaarreedd bbyypphhoottoocchheemmiiccaallttrraannssffoorrmmaattiioonn ooff ppyyrriiddiinniiuumm ssaallttss aarree kkeeyyiinntteerrmmeeddiiaatteess uusseedd ffoorrtthheettoottaallssyynntthheessiissooffsseevveerraallaammininooccyyccllooppeennttiittoollss ((SScchheemmee11))[[11–-44]]
PQT6 reactor was placed inside the UV photochemical reactor
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Summary
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