Abstract

The hangover is the most commonly reported negative consequence of alcohol use with several studies reporting the detrimental consequences of hangover on health, economy, and society. Research has emphasized the socioeconomic consequences of experiencing these physical and psychological symptoms in relation to absenteeism, increased risk of having accidents and injuries, and impairment of daily activities, such as job performance and driving a car. During the 10th Alcohol Hangover Research Group meeting, held on 29 April 2018, in Utrecht, The Netherlands, aspects of alcohol hangover were presented with regards to determinants, biological and cognitive consequences and potential treatments. Precursory and posterior factors influencing alcohol hangover, including biological, psychological, behavioral, metabolic aspects, cognitive functioning, and the role of the immune system in the development of alcohol hangover, were presented. In addition, potential preventive measures and treatments of alcohol hangover to reduce the adverse consequences of alcohol consumption and hangover symptoms were discussed. One study revealed that an average of 24% of social and heavy drinkers claimed not to experience hangover symptoms across time. Another study showed that food intake (either healthy or junk food) had no significant impact on next-day hangover severity. Research examining cognitive and psychomotor functioning during hangover revealed impairments in collective problem solving and response inhibition, but not attentional bias towards alcohol-related cues. The alcohol hangover state further significantly impaired driving performance, even for a short commute to work. With regard to the pathology of the alcohol hangover, research was presented that demonstrated increases in saliva cytokine concentrations confirming drinking alcohol and the hangover phase are both associated with an immune response. Other presentations discussed that scientific literature shows that there are no effective hangover treatments available yet. However, although promising, new hangover treatments are currently in development. Taken together, at the 10th Alcohol Hangover Research Group meeting, a comprehensive overview of the causes, consequences, and potential treatments of the alcohol hangover was presented.

Highlights

  • Alcohol hangover is the most commonly experienced consequence of alcohol consumption [1]and is defined as the combination of negative mental and physical symptoms which can be experienced after a single episode of alcohol consumption, starting when blood alcohol concentration (BAC) approaches zero [2,3]

  • Increased center line crossing and time off road, reflecting poorer control, were seen for the residual alcohol group. These results show that the alcohol hangover state significantly impairs driving performance, even for a relatively short ‘commute to work’ and despite a greater subjective effort being made by drivers

  • Various aspects of alcohol hangover were discussed during the 10th Alcohol Hangover Research Group (AHRG) meeting

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Summary

Introduction

Alcohol hangover is the most commonly experienced consequence of alcohol consumption [1]. Is defined as the combination of negative mental and physical symptoms which can be experienced after a single episode of alcohol consumption, starting when blood alcohol concentration (BAC) approaches zero [2,3]. To support alcohol hangover related research, in 2010 the Alcohol Hangover Research Group (AHRG). Was established to promote international research and collaboration, review and enhance methodological procedures and increase general knowledge of alcohol hangover. AHRG meetings have been held to discuss the causes, consequences and treatment of the alcohol hangover [5,6,7,8,9]. The present proceedings provide a synopsis of the 10th AHRG meeting, held on.

Precursory Factors of Alcohol Hangover
Behavioral Aspects of Alcohol Hangover
Cognitive Effects of Alcohol Hangover
Biological Effects of Alcohol Hangover
Interventions and Treatments for Alcohol Hangover
Findings
Discussion
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