Problems with clinical trials in general practice — a double‐blind comparison of cream containing miconazole and hydrocortisone with hydrocortisone alone in the treatment of intertrigo

Abstract

SummaryA double‐blind comparative study between 1 % hydrocortisone cream and a combination of 1% hydrocortisone cream and 2% miconazole cream has highlighted some of the problems with this type of research in general practice. The collection of adequate patient numbers within a predefined time scale proved a major problem. However, the study demonstrated the safety and efficacy of both these preparations in the treatment of intertrigo.