Abstract
The problems facing a pathologist or anatomist who wishes to embark on computer-assisted reconstruction of structures seen in serial light microscope sections are reviewed. They are illustrated by comparing a reconstruction of a bronchial gland made by cutting out polystyrene sheets with models generated by four computer-assisted systems, i.e. the IBAS 2000 system, the SSRCON (MRC) system, the AT-Videoplan system and the CHD (Cookson, Holman, Dykes) system. It is obvious that computer-assistance cannot solve the preparation problems of three-dimensional reconstruction (3DR) and that choosing a computer-assisted system is fraught with difficulties. It is recommended that intending purchasers of computer-assisted 3DR systems prepare material in advance to try out on the systems they are considering.
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