Problems of depression and auto-aggressive manifestations in cancer patients

Abstract

Purpose. To study the clinical features of non-psychotic depression and autoaggressive manifestations (AM) in cancer patients and to identify ways of improving the quality of medical support indicated patients. Materials and methods. Clinical and paraclinical methods xamined 30 women with tumors of the female reproductive system ІІ-ІІІ stages: cervical cancer (C52) cancer of the vagina (C53) at age of 42 to 65 years (mean 47±0,5), who asked to diagnostic and treatment in the Department of radiotherapy of the National cancer Institute in a month or more after the establishing of cancer diagnosis, and outpatients treated with depressive complaints and the AM, to the Department of psychiatry and narcology of Bogomolets National Medical University. These patients are examined by oncologists, gynecologists, internists, neurologists, psychiatrists, endocrinologists, using clinical-psychopathological, clinical-dynamic, catamnestic, paraclinical methods, followed by radiation therapy, chemoradio therapy, psychopharmacotherapiy and psychotherapy. Catamnestic observation lasted from one to two years. Results and discussion. AM was diagnosed in 30 of the women surveyed in the cancer (C52; C53) with depression underneurotic and stress-related disorders (ICD -10; F4). Highlighted anxious (n = 12; 40%), astheno-subdepressivee (n = 7; 23,3%), phobic (n = 6; 20%), dysphoric (n = 5; 16.7%) syndromes. About half of the 12 (40%) patients had accentuation of character, disharmony of personality and psychopathic traits. Thus, patients with the cancer dominated by anxious-depressive, subdepressive and phobic disorders, rarely dysphoric disorder, which was confirmed by the aggregation (p <0.05; p <0,05-0,01). Conclusion. In cancer patients with cancer (C52, C53) with depression and isdominated by AM, anxiety-depressive, astheno-subdepressive and phobic disorders, rarely dysphoric disorder (ICD-10; F4) that worsen the medical condition, prognosis and treatment of the underlying disease, reduce the quality of life of patients, increase the risk of suicide. The solution of this problem requires integration of efforts oncological, psychological, psychiatric and other institutions in the unifiedstate strategy.