Problem of Pathogenesis of Chronic Hypertrophic Gastritis

Abstract

Inflammations of the stomach may be divided roughly into acute and chronic. Among the chronic cases, some are specific in nature, as tuberculosis and parasitic infestations; these are rare, leaving a majority which are of obscure origin. A further division may be made on a basis of tendency toward hypertrophy or atrophy. Hypertrophy is found more often than atrophy in chronic gastritis; this report is concerned chiefly with the hypertrophic form. Knowledge concerning the pathogenesis of chronic hypertrophic gastritis is seriously incomplete. The solution of the problem will require well integrated study by a team composed of internist, gastroscopist, surgeon, radiologist, and pathologist. The study should be carefully planned in advance, rigidly controlled, and carried out over an extended period of time, with both observational and experimental technics. Chronic hypertrophic gastritis may be a type of reaction to a number of different pathogenetic forces. Among the possible etiologic factors that have be...