Abstract
As a typical deoxyribonucleic acid (DNA) base with diverse amino/imino groups, guanine has remarkable Raman activity; however, its Raman modes are largely forbidden in solid Raman measurements, which hinders full understanding of the chemistry of such DNA bases. Here a study on surface-enhanced Raman scattering (SERS) of guanine is reported by employing colloidal silver nanoparticles modified on the silver electrode as substrate. High-quality SERS spectra with potential dependence were obtained, shedding light on the varying adsorption behavior of guanine on the nano-surface. High-quality SERS spectra have also been obtained for picolinic acid molecules. The good stability and homogeneous size distribution of silver nanoparticle coatings provide a highly SERS-active substrate for detecting DNA-bases and probing their local interactions.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
