Abstract
The phytochemical screening of the crude methanolic stem extracts of Cassia javanica plant showed the presence of different classes of organic compounds like alkaloids, tannins, flavonoids, saponins, phlobatanins, steroids, anthraquinone and cardiac glycoside. The starching frequencies of these functional groups were determined from FT-IR spectroscopic data. The crude and their fractions were examined for antibacterial potential against Klebsiella pneumoniae and Proteus mirabilis. The antibacterial assay showed maximum zone of inhibition for ethyl acetate fraction, i.e. 20 mm against Proteus mirabilis and 18 mm against Klebsiella pneumoniae in the comparison with Levofloxacin used as standard (40 mm). Meanwhile for methanolic crude extract, the inhibition zone was recorded 14 mm against Klebsiella pneumoniae and 22 mm against Proteus mirabilis. The minimum inhibitory concentrations and minimum bactericidal concentrations were recorded as 187.5 µg ml−1 against Proteus mirabilis and 93.75 µg ml−1 against Klebsiella pneumoniae. The scavenging free radical assay was noted as 69.61% at the concentration of 100 ppm.
Highlights
Plants sustain life on Earth, as they provide all the basic needs of life like food, shelter and medicines etc. [1,2]
Different fractions of crude extract of C. javanica showed different chemical profile; e.g. in crude extract tannins, flavonoids, phlobatanins and anthraquinone were present while cardiac glycoside does not express its presence. n-hexane fraction contains tannins and steroids while alkaloids, flavonoids, steroids, cardiac glycoside, anthraquinone and phlobatanins were absent in n-hexane fraction
The yields of phytochemicals present in C. javanica indicate that a total of 9% of the dry mass of C. javanica is composed of active phytochemicals/metabolites
Summary
Plants sustain life on Earth, as they provide all the basic needs of life like food, shelter and medicines etc. [1,2]. Plants sustain life on Earth, as they provide all the basic needs of life like food, shelter and medicines etc. Plants which are used in order to cure or prevent a disease or to alter pathological and physiological process, or any plant working as a source of drugs or their precursors are known as medicinal plants [3,4]. Most herbal products are present in the form of leaf powder, pills and paste for the treatment of several diseases in humans [5].
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