Probing hydrogen-bonding patterns in cocrystals of amides and triarylphosphine oxides using high-resolution solid-state 31P NMR spectroscopy

Abstract

The isotropic 31P chemical shift for hydrogen-bonded cocrystals formed between aryl sulfonamides and triarylphosphine oxides shows a linear corrleation with the number of hydrogen-bonds, N–H ⋯ O–P, formed by each triarylphosphine oxide fragment; this result can now be applied as a means of deriving information on the hydrogen-bonding patterns in related cocrystals of unknown structure.