Abstract
BackgroundThe myocardium exhibits heterogeneous nature due to scarring after Myocardial Infarction (MI). In Cardiac Magnetic Resonance (CMR) imaging, Late Gadolinium (LG) contrast agent enhances the intensity of scarred area in the myocardium.MethodsIn this paper, we propose a probability mapping technique using Texture and Intensity features to describe heterogeneous nature of the scarred myocardium in Cardiac Magnetic Resonance (CMR) images after Myocardial Infarction (MI). Scarred tissue and non-scarred tissue are represented with high and low probabilities, respectively. Intermediate values possibly indicate areas where the scarred and healthy tissues are interwoven. The probability map of scarred myocardium is calculated by using a probability function based on Bayes rule. Any set of features can be used in the probability function.ResultsIn the present study, we demonstrate the use of two different types of features. One is based on the mean intensity of pixel and the other on underlying texture information of the scarred and non-scarred myocardium. Examples of probability maps computed using the mean intensity of pixel and the underlying texture information are presented. We hypothesize that the probability mapping of myocardium offers alternate visualization, possibly showing the details with physiological significance difficult to detect visually in the original CMR image.ConclusionThe probability mapping obtained from the two features provides a way to define different cardiac segments which offer a way to identify areas in the myocardium of diagnostic importance (like core and border areas in scarred myocardium).
Highlights
Patients who have suffered but survived myocardial infarction (MI) may subsequently suffer a possibly disabling or fatal cardiac arrhythmia
We propose a technique for transforming the scarred myocardium in the Cardiac Magnetic Resonance (CMR) image to a probability map to indicate varying degrees of its functioning capabilities: where high and low probabilities will indicate the scarred tissue and normal tissue, respectively
In this paper, a new technique has been proposed for enhanced visualization of scarred myocardium in Late Gadolinium (LG) enhanced CMR images using probability mapping
Summary
Patients who have suffered but survived myocardial infarction (MI) may subsequently suffer a possibly disabling or fatal cardiac arrhythmia. Late Gadolinium (LG) enhanced Cardiac Magnetic Resonance imaging (CMR) is used for assessing morphology of the myocardium in patients after MI. The myocardial muscle fibers are completely dead at the core area of the scar. The core area does not react to the electrical signals propagating through the heart muscle telling the heart to contract. The electrical signals will be disturbed in these areas possibly causing reentries and sometimes arrhythmias. The latter gives us reason to believe that the border areas are a very important part of the scar, and good ways of defining and visualizing border areas would be beneficial in many situations. In Cardiac Magnetic Resonance (CMR) imaging, Late Gadolinium (LG) contrast agent enhances the intensity of scarred area in the myocardium
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