Abstract

Psoriasis is a chronic, relapsing disease. Topical treatment with local corticosteroids plays a significant role in the management of psoriasis. In the current medical practice, the so called reactive treatment approach, which treats active symptoms is used. However, using this method, the relapse of the symptoms is inevitable. Relapses may affect unfavourably the quality of life of the patients, therefore reducing the frequency of the relapses is an important therapeutic target. A proactive treatment approach means that previously symptomatic areas of the skin are treated at specific times to maintain remission. Clinical studies with a high level of evidence using a fixed combination of calcipotriol and betamethasone dipropionate foam have shown that proactive treatment administered two times weekly can prolong the time until the first relapse. Furthermore, this treatment method may reduce the frequency of the relapses and may increase the number of days spent in remission without any major side effects.

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