Abstract

Patients with atypical hemolytic uremic syndrome (aHUS) may require ongoing treatment of varying duration. The C5 complement inhibitor eculizumab provides transformative benefits in aHUS; however, knowledge gaps remain regarding treatment patterns/preferences. To address this, we sought to characterize real-world eculizumab use, disease triggers, dialysis and plasma exchange/infusion (PE/PI) in patients with aHUS using US claims data.

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