Abstract

A fluorescent probe (terephthalic acid) has been used for rapid assessment of the ability of amino acids and their derivatives to accept and/or promote the formation of HO˙ radicals in the Cu2+–H2O2, Fe2+/EDTA–H2O2 systems. In the concentration range of 0.005-30 mM, the amino acids are arranged in the following series according to the increase in IC50: Trp 2 : 1 (≥1 : 1 for His). Cys is also a prooxidant in the Fe2+/EDTA system.

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