Abstract
Pro- and anti-apoptotic signaling pathways in poliovirus-infected neuronal cells
Highlights
Infectious diseases of the nervous system: pathogenesis and worldwide impact Roberto Bruzzone, Monique Dubois-Dalcq, Georges E Grau, Diane E Griffin and Krister Kristensson Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here.
We have shown that mitochondrial dysfunction in PVinfected human neuronal IMR5 cells was dependent on the protein Bax, a proapoptotic member of the Bcl-2 family
Bax activation was mediated by c-Jun NH2-terminal kinase (JNK) phosphorylation after PV infection [1]
Summary
Infectious diseases of the nervous system: pathogenesis and worldwide impact Roberto Bruzzone, Monique Dubois-Dalcq, Georges E Grau, Diane E Griffin and Krister Kristensson Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. . Address: 1Biology of Enteric Viruses, Institut Pasteur, 75015 Paris, France and 2INSERM V841, 94010 Créteil, France Email: Bruno Blondel* - bblondel@pasteur.fr * Corresponding author from Infectious diseases of the nervous system: pathogenesis and worldwide impact Paris, France.
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