Abstract

Abstract Investigation into hormone antibody interactions have demonstrated that antibodies can inhibit or potentiate both exogenous and endogenous hormone activity, raising the possibility that the immune system can be used to improve animal production efficiency. This paper reviews the physiology of antibody-manipulated hormone activity in growth regulation, particularly in relation to hormone enhancement; possible mechanisms for such a phenomenon are discussed. Lastly, it is now clear that potentiation and inhibition of peptide hormones may occur in vivo and this is reviewed in terms of growth factor bioavailability. Parallels are made between this natural means of regulation with antibody-mediated regulation.

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