Abstract
‘‘All true universities, whether public or private, are public trusts designed to advance knowledge by safeguarding the free inquiry of impartial teachers and scholars. Their independence is essential because the university provides knowledge not only to its students, but also to the public agency in need of expert guidance and the general society in need of greater knowledge;... these latter clients have a stake in disinterested professional opinion, stated without fear or favor, which the institution is morally required to respect.’’ — American Association of University Professors [1]
Highlights
‘‘All true universities, whether public or private, are public trusts designed to advance knowledge by safeguarding the free inquiry of impartial teachers and scholars
Some sectors of the international clinical trials enterprise have begun to respond to the gathering crisis of confidence
Public Library of Science (PLoS)’ newest openaccess journal, PLoS Clinical Trials, is committed to publishing the results of ethically and scientifically sound clinical trials without regard to their direction or perceived importance [15]. These developments are encouraging, notwithstanding a continued absence of consensus about the specific identifying information that should be registered for each clinical trial, the format and detail with which trial results should be deposited, and how much of, and at what point, this information should be publicly accessible [16]
Summary
‘‘All true universities, whether public or private, are public trusts designed to advance knowledge by safeguarding the free inquiry of impartial teachers and scholars. Not so encouraging is the significant variation across the academic community in standards that protect the right and duty of academic investigators to take appropriate responsibility for the design, analysis, and reporting of clinical research, especially clinical trials sponsored by industry [17,18].
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