Abstract
Objective: The aim of this paper is to review the literature on the pharmacological action of bisphosphonates and their performance on the facial bone structures, correlating them with different areas of the maxillofacial surgery. Literature review and Final considerations: Bisphosphonate drugs are used for the treatment and prevention of various diseases by acting directly on bone remodeling and vascularization. These drugs affect the bone remodeling by means of bone decreasing resorption by different mechanisms, acting on osteoclasts mainly, inhibiting and reducing its activity. Bisphosphonates have a high affinity for hydroxyapatite bone surface, which causes greater accumulation of mineral on regions with high bone activity. The use of certain formulations of these drugs has been associated with the development of bone necrosis in maxilla and mandible. Recent studies show that the use of bisphosphonates can perform as an adjunct in the treatment of patients undergoing oral and maxillofacial surgical procedures such as distraction osteogenesis, bone grafts and implantology. Key words: Osteoporosis. Osseointegration. Dental implantation. Bisphosphonates. Osteonecrosis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
