Abstract
Copyright: © 2013 Hesselink JMK. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Our analgesic armamentarium is rooted in pharmaceuticals. Drugs initially protected by patent, new chemical entities (NCE), molecules which never existed on earth until medical chemists synthesized them. Within the realm of this type of analgesics there are just a handful of variations: non-steroidal anti-inflammatory drugs (NSAID’s such as ibuprofen), opioids (tramadol, oxycontin), antidepressants (amitriptyline, venlafaxin), anti-epileptics (gabapentine, pregabalin), paracetamol/acetaminophen and a waste basket of various old coanalgesics such as baclofen. Cannabinoids are for the courageous pain physicians only, although there are many safety reasons to prefer Cannabinoids over opiates.
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