Primary Tumor Sidedness, RAS and BRAF Mutations and MSI Status as Prognostic Factors in Patients with Colorectal Liver Metastases Treated with Surgery and Thermal Ablation: Results from AmCORE

Petrousjka Van Den Tol,Madelon Dijkstra,Sanne Nieuwenhuizen,Robbert S Puijk,Florentine E.F Timmer,Bart Geboers,Evelien A.C Schouten,Jip Opperman,Hester J Scheffer,Jan J.J De Vries,Kathelijn S Versteeg,Birgit I Lissenberg-Witte,Martijn R Meijerink

doi:10.1016/j.ejso.2021.12.197

Primary Tumor Sidedness, RAS and BRAF Mutations and MSI Status as Prognostic Factors in Patients with Colorectal Liver Metastases Treated with Surgery and Thermal Ablation: Results from AmCORE

Petrousjka Van Den Tol, Madelon Dijkstra + Show 11 more

https://doi.org/10.1016/j.ejso.2021.12.197

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Journal: European Journal of Surgical Oncology

Publication Date: Feb 1, 2022

Affiliation: Amsterdam University Medical Centers, Noordwest Ziekenhuisgroep

#Microsatellite Instability Status #V-raf Murine Sarcoma Viral Oncogene + Show 8 more

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Abstract

Background: The aim of this study was to assess primary tumor sidedness of colorectal cancer (CRC), rat sarcoma viral oncogene homolog (RAS) and v-raf murine sarcoma viral oncogene homolog B (BRAF) mutations and microsatellite instability (MSI) status as prognostic factors predicting complications, survival outcomes and local tumor progression (LTP) following surgery and thermal ablation in patients with colorectal liver metastases (CRLM).

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