Abstract
Primary Squamous Carcinoma of Thyroid(PSCT) is a rare but distinct clinicopathological disease. Due to the paucity, optimal intervention strategy has not been established yet. PSCT was once viewed as radioresistant. Here we present a rare case of PSCT in which postoperative radiotherapy was effective for local control and maintenance of progression free survival (PFS) of more than 10 months after R2 resection. Our case will help to identify the role of adjuvant radiotherapy in the treatment of PSCT and extend our understanding of this rare thyroid carcinoma.
Highlights
PSCT is a distinct disease seldom encountered in clinical practice
We present a case of PSCT in which R2 resection followed by adjuvant radiotherapy attained a favorable progression free survival (PFS) of at least 10 months
PSCT bears a grim prognosis with shortest reported survival of 17 days [5]
Summary
PSCT is a distinct disease seldom encountered in clinical practice. Generally, it has an aggressive behavior with a median survival of 9.0 months [1]. We present a case of PSCT in which R2 resection followed by adjuvant radiotherapy attained a favorable PFS of at least 10 months. A regular 2.5 cm × 2.0 cm and 5.0 cm × 3.0 cm mass was palpated in the right and left lobe of thyroid respectively without tenderness, moving up and down with swallowing.
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