Abstract

The mouse β 1- adrenergic receptor was isolated from a genomic library and cloned into pBluescript SK −. Characterization of the clone revealed an open reading frame which encodes a predicted protein of 466 amino acids. The mouse β 1 receptor is 92.7% identical to the human sequence, 98.5% identical to the rat sequence, and contains a consensus site for N-linked glycosylation at Asn-15 and a cAMP-dependent protein kinase phosphorylation site at Ser-301.

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