Primary Stromal Sarcoma of the Ovary: A Case Report

Abstract

To report and review the management of a rare primary stromal sarcoma of the ovary. We report a rare type of ovarian malignancy that occurred in a 60-year-old female. She visited our department due to lower abdominal discomfort. Ultrasound and abdominal computed tomography showed a heterogeneous mass over the left adnexa without ascites or lymphadenopathy. During surgery, we found an irregular ovarian tumor arising from the left adnexa with severe adhesion at the cul-de-sac. Frozen sections indicated a malignancy, so debulking surgery was performed. The final histopathologic findings showed a low- grade stromal sarcoma of the left ovary with omental and uterine metastasis. Adjuvant chemotherapy with a combination of 70 mg/m 2 epirubicin, 50 mg/m 2 cisplatin, and 6 g ifosfamide was given. Unfortunately, lymph node metastasis and tumor recurrence were noted at the end of the third course of chemotherapy. The prognosis for sarcoma is poor and these tumors are always radio-resistant. Adjuvant chemotherapy with doxorubicin and other agents may provide some response. Unfortunately, we found multiple intra-abdominal metastases in the patient. The disease course was 10 months.